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Deoxysugars as Antituberculars and Alpha-Mannosidase Inhibitors
A promising modified sugar molecule was identified which was active against multidrug-resistant (MDR) strains of Mycobacterium tuberculosis, suggesting involvement of a new target. The compound was demonstrated to be bactericidal, inhibited the growth of M. tuberculosis in mice, and targeted alpha-m...
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| Autores principales: | , , , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
American Society for Microbiology
2014
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4068473/ https://ncbi.nlm.nih.gov/pubmed/24687500 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02715-13 |
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