VEGF Inhibits Tumor Cell Invasion and Mesenchymal Transition Through a MET/VEGFR2 Complex

Inhibition of VEGF signaling leads to a pro-invasive phenotype in mouse models of glioblastoma multiforme (GBM) and in a subset of GBM patients treated with bevacizumab. Here we demonstrate that vascular endothelial growth factor (VEGF) directly and negatively regulates tumor cell invasion through e...

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Hauptverfasser: Lu, Kan V., Chang, Jeffrey P., Parachoniak, Christine A., Pandika, Melissa M., Aghi, Manish K., Meyronet, David, Isachenko, Nadezda, Fouse, Shaun D., Phillips, Joanna J., Cheresh, David A., Park, Morag, Bergers, Gabriele
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2012
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4068350/
https://ncbi.nlm.nih.gov/pubmed/22789536
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ccr.2012.05.037
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