Novel transcripts from a distinct promoter that encode the full-length AKT1 in human breast cancer cells

BACKGROUND: The serine-threonine kinase AKT1 plays essential roles during normal mammary gland development as well as the initiation and progression of breast cancer. AKT1 is generally considered a ubiquitously expressed gene, and its persistent activation is transcriptionally controlled by regulato...

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Bibliographic Details
Main Authors: Schmidt, Jeffrey W, Wehde, Barbara L, Sakamoto, Kazuhito, Triplett, Aleata A, West, William W, Wagner, Kay-Uwe
Format: Artigo
Language:Inglês
Published: BioMed Central 2014
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4068023/
https://ncbi.nlm.nih.gov/pubmed/24628780
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-14-195
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