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Throwing the Cancer Switch: Reciprocal Roles of Polycomb and Trithorax Proteins

The discovery that cancer can be governed above and beyond the level of our DNA presents a new era for designing therapies that reverse the epigenetic state of a tumor cell. Understanding how altered chromatin dynamics leads to malignancy is essential for controlling tumor cells while sparing normal...

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Détails bibliographiques
Auteur principal: Mills, Alea A.
Format: Artigo
Langue:Inglês
Publié: 2010
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4068012/
https://ncbi.nlm.nih.gov/pubmed/20865010
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrc2931
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