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Throwing the Cancer Switch: Reciprocal Roles of Polycomb and Trithorax Proteins
The discovery that cancer can be governed above and beyond the level of our DNA presents a new era for designing therapies that reverse the epigenetic state of a tumor cell. Understanding how altered chromatin dynamics leads to malignancy is essential for controlling tumor cells while sparing normal...
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4068012/ https://ncbi.nlm.nih.gov/pubmed/20865010 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrc2931 |
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