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Kinetic framework of spindle assembly checkpoint signaling
The mitotic spindle assembly checkpoint (SAC) delays anaphase onset until all chromosomes have attached to both spindle poles(1,2). Here, we investigated SAC signaling kinetics in response to acute detachment of individual chromosomes using laser microsurgery. Most detached chromosomes delayed anaph...
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| Auteurs principaux: | , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2013
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4067996/ https://ncbi.nlm.nih.gov/pubmed/24096243 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncb2842 |
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