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Kinetic framework of spindle assembly checkpoint signaling

The mitotic spindle assembly checkpoint (SAC) delays anaphase onset until all chromosomes have attached to both spindle poles(1,2). Here, we investigated SAC signaling kinetics in response to acute detachment of individual chromosomes using laser microsurgery. Most detached chromosomes delayed anaph...

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Detalhes bibliográficos
Main Authors: Dick, Amalie E., Gerlich, Daniel W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4067996/
https://ncbi.nlm.nih.gov/pubmed/24096243
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncb2842
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