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Two different approaches for pharmacokinetic modeling of exhaled drug concentrations

Online measurement of drug concentrations in patient's breath is a promising approach for individualized dosage. A direct transfer from breath- to blood-concentrations is not possible. Measured exhaled concentrations are following the blood-concentration with a delay in non-steady-state situati...

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Bibliographic Details
Main Authors: Kreuer, S., Hauschild, A., Fink, T., Baumbach, J. I., Maddula, S., Volk, Th.
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2014
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4067807/
https://ncbi.nlm.nih.gov/pubmed/24957852
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep05423
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