A Cell-Based High-Throughput Screen Addressing 3′UTR-Dependent Regulation of the MYCN Gene

Neuroblastoma is the most common extracranial solid tumor of infancy. Amplification of MYCN oncogene is found in approximately 20 % of all neuroblastoma patients and correlates with advanced disease stages, rapid tumor progression, and poor prognosis, making this gene an obvious therapeutic target....

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Main Authors: Sidarovich, Viktoryia, Adami, Valentina, Quattrone, Alessandro
Format: Artigo
Jezik:Inglês
Izdano: Springer US 2014
Teme:
Research
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4067544/
https://ncbi.nlm.nih.gov/pubmed/24515800
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12033-014-9739-z
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