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Gipc1 has a dual role in Vangl2 trafficking and hair bundle integrity in the inner ear

Vangl2 is one of the central proteins controlling the establishment of planar cell polarity in multiple tissues of different species. Previous studies suggest that the localization of the Vangl2 protein to specific intracellular microdomains is crucial for its function. However, the molecular mechan...

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Autors principals: Giese, Arnaud P., Ezan, Jérome, Wang, Lingyan, Lasvaux, Léa, Lembo, Frédérique, Mazzocco, Claire, Richard, Elodie, Reboul, Jérome, Borg, Jean-Paul, Kelley, Matthew W., Sans, Nathalie, Brigande, John, Montcouquiol, Mireille
Format: Artigo
Idioma:Inglês
Publicat: Company of Biologists 2012
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4067280/
https://ncbi.nlm.nih.gov/pubmed/22991442
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.074229
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