(-)-Phenserine Attenuates Soman-Induced Neuropathology

Organophosphorus (OP) nerve agents are deadly chemical weapons that pose an alarming threat to military and civilian populations. The irreversible inhibition of the critical cholinergic degradative enzyme acetylcholinesterase (AChE) by OP nerve agents leads to cholinergic crisis. Resulting excessive...

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Bibliographic Details
Main Authors: Chen, Jun, Pan, Hongna, Chen, Cynthia, Wu, Wei, Iskandar, Kevin, He, Jeffrey, Piermartiri, Tetsade, Jacobowitz, David M., Yu, Qian-Sheng, McDonough, John H., Greig, Nigel H., Marini, Ann M.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2014
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4067273/
https://ncbi.nlm.nih.gov/pubmed/24955574
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0099818
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