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Early-onset Formation of Parenchymal Plaque Amyloid Abrogates Cerebral Microvascular Amyloid Accumulation in Transgenic Mice

The fibrillar assembly and deposition of amyloid β (Aβ) protein, a key pathology of Alzheimer disease, can occur in the form of parenchymal amyloid plaques and cerebral amyloid angiopathy (CAA). Familial forms of CAA exist in the absence of appreciable parenchymal amyloid pathology. The molecular in...

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Bibliografiske detaljer
Main Authors: Xu, Feng, Kotarba, AnnMarie E., Ou-Yang, Ming-Hsuan, Fu, Ziao, Davis, Judianne, Smith, Steven O., Van Nostrand, William E.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4067220/
https://ncbi.nlm.nih.gov/pubmed/24828504
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.536565
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