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Early-Onset Subicular Microvascular Amyloid and Neuroinflammation Correlate With Behavioral Deficits in Vasculotropic Mutant APP Transgenic Mice

Cerebral microvascular amyloid β protein (Aβ) deposition and associated neuroinflammation are increasingly recognized as an important component leading to cognitive impairment in Alzheimer’s disease and related cerebral amyloid angiopathy (CAA) disorders. Transgenic mice expressing the vasculotropic...

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Hlavní autoři: Xu, Feng, Grande, Alicia M., Robinson, John K., Previti, Mary Lou, Vasek, Michael, Davis, Judianne, Van Nostrand, William E.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2007
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1949338/
https://ncbi.nlm.nih.gov/pubmed/17331655
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuroscience.2007.01.043
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