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Casein Kinase II Regulation of the Hot1 Transcription Factor Promotes Stochastic Gene Expression

In Saccharomyces cerevisiae, Hog1 MAPK is activated and induces a transcriptional program in response to hyperosmotic stress. Several Hog1-responsive genes exhibit stochastic transcription, resulting in cell-to-cell variability in mRNA and protein levels. However, the mechanisms governing stochastic...

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Detalhes bibliográficos
Main Authors: Burns, Laura T., Wente, Susan R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4067201/
https://ncbi.nlm.nih.gov/pubmed/24817120
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.561217
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