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Role of metal ions in the cognitive decline of Down syndrome
Down syndrome (DS), caused by trisomy of whole or part of chromosome 21 is the most common mental impairment. All people with DS suffer from cognitive decline and develop Alzheimer’s disease (AD) by the age of 40. The appearance of enlarged early endosomes, followed by Amyloid βpeptide deposition, t...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Frontiers Media S.A.
2014
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4066992/ https://ncbi.nlm.nih.gov/pubmed/25002847 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnagi.2014.00136 |
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