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Role of metal ions in the cognitive decline of Down syndrome
Down syndrome (DS), caused by trisomy of whole or part of chromosome 21 is the most common mental impairment. All people with DS suffer from cognitive decline and develop Alzheimer’s disease (AD) by the age of 40. The appearance of enlarged early endosomes, followed by Amyloid βpeptide deposition, t...
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| Auteurs principaux: | , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Frontiers Media S.A.
2014
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4066992/ https://ncbi.nlm.nih.gov/pubmed/25002847 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnagi.2014.00136 |
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