Disruption of mitotic arrest precedes precocious differentiation and transdifferentiation of pregranulosa cells in the perinatal Wnt4 mutant ovary

Mammalian sex determination is controlled by antagonistic pathways that are initially co-expressed in the bipotential gonad and subsequently become male- or female-specific. In XY gonads, testis development is initiated by upregulation of Sox9 by SRY in pre-Sertoli cells. Disruption of either gene l...

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Bibliografiske detaljer
Main Authors: Maatouk, Danielle M., Mork, Lindsey, Chassot, Anne-Amandine, Marie-Christine, Chaboissier, Capel, Blanche
Format: Artigo
Sprog:Inglês
Udgivet: 2013
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4066978/
https://ncbi.nlm.nih.gov/pubmed/24036309
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2013.08.026
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