The Mitochondrial Fission Receptor MiD51 Requires ADP as a Cofactor

Mitochondrial fission requires recruitment of dynamin-related protein 1 (Drp1) to the mitochondrial surface and activation of its GTP-dependent scission function. The Drp1 receptors MiD49 and MiD51 recruit Drp1 to facilitate mitochondrial fission, but their mechanism of action is poorly understood....

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Bibliographic Details
Main Authors: Losón, Oliver C., Liu, Raymond, Rome, Michael E., Meng, Shuxia, Kaiser, Jens T., Shan, Shu-ou, Chan, David C.
Format: Artigo
Language:Inglês
Published: 2014
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4066849/
https://ncbi.nlm.nih.gov/pubmed/24508339
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2014.01.001
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