Effects of camptothecin derivatives and topoisomerase dual inhibitors on Trypanosoma cruzi growth and ultrastructure

BACKGROUND: Trypanosoma cruzi is the etiological agent of Chagas’ disease that is an endemic disease in Latin America and affects about 8 million people. This parasite belongs to the Trypanosomatidae family which contains a single mitochondrion with an enlarged region, named kinetoplast that harbors...

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Bibliografiske detaljer
Main Authors: Lacombe, Otto Kischlat, Zuma, Aline Araujo, da Silva, Camila Cristina, de Souza, Wanderley, Motta, Maria Cristina M
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2014
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4066697/
https://ncbi.nlm.nih.gov/pubmed/24917086
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1477-5751-13-11
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