Trypanosoma cruzi proliferation and differentiation are blocked by topoisomerase II inhibitors.

Bacterial topoisomerase II inhibitors (ofloxacin and its commercial derivative Tarivid, nalidixic acid, and novobiocin) were tested as blockers of Trypanosoma cruzi differentiation and proliferation. The transformation of either epimastigotes into metacyclic trypomastigotes or amastigotes into trypo...

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Main Authors: Gonzales-Perdomo, M, de Castro, S L, Meirelles, M N, Goldenberg, S
Format: Artigo
Jezik:Inglês
Izdano: 1990
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC171910/
https://ncbi.nlm.nih.gov/pubmed/2178335
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