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A role for hydrogen bonding in DNA recognition by the non–classical CCHHC type zinc finger, NZF–1
The non-classical zinc finger protein, Neural Zinc Finger Factor-1, contains six Cys(2)His(2)Cys domains. All three cysteines and the second histidine directly bind Zn(II). Using a combination of mutagenesis, metal coordination and DNA binding studies, we report that the first histidine is involved...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4066409/ https://ncbi.nlm.nih.gov/pubmed/24820620 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c4mb00246f |
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