Cdc42 is required for EGF-stimulated protrusion and motility in MTLn3 carcinoma cells

Cdc42 plays a central role in regulating the actin cytoskeleton and maintaining cell polarity. Here, we show that Cdc42 is crucial for epidermal growth factor (EGF)-stimulated protrusion in MTLn3 carcinoma cells. When stimulated with EGF, carcinoma cells showed a rapid increase in activated Cdc42 th...

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Hlavní autoři: El-Sibai, Mirvat, Nalbant, Peri, Pang, Huan, Flinn, Rory J., Sarmiento, Corina, Macaluso, Frank, Cammer, Michael, Condeelis, John S., Hahn, Klaus M., Backer, Jonathan M.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2007
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4066376/
https://ncbi.nlm.nih.gov/pubmed/17855387
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.005942
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