Role of Transcription Factor Acetylation in Diabetic Kidney Disease

Nuclear factor (NF)-κB and signal transducer and activator of transcription 3 (STAT3) play a critical role in diabetic nephropathy (DN). Sirtuin-1 (SIRT1) regulates transcriptional activation of target genes through protein deacetylation. Here, we determined the roles of Sirt1 and the effect of NF-κ...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Liu, Ruijie, Zhong, Yifei, Li, Xuezhu, Chen, Haibing, Jim, Belinda, Zhou, Ming-Ming, Chuang, Peter Y., He, John Cijiang
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Diabetes Association 2014
Schlagworte:
Complications
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4066331/
https://ncbi.nlm.nih.gov/pubmed/24608443
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db13-1810
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