GEF-H1 controls microtubule-dependent sensing of nucleic acids for antiviral host defenses

Detailed understanding of the signaling intermediates that confer the sensing of intracellular viral nucleic acids for induction of type I interferons is critical for strategies to curtail viral mechanisms that impede innate immune defenses. Here we show that the activation of the microtubule-associ...

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Hlavní autoři: Chiang, Hao-Sen, Zhao, Yun, Song, Joo-Hye, Liu, Song, Wang, Ninghai, Terhorst, Cox, Sharpe, Arlene H., Basavappa, Megha, Jeffrey, Kate L., Reinecker, Hans-Christian
Médium: Artigo
Jazyk:Inglês
Vydáno: 2013
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4066330/
https://ncbi.nlm.nih.gov/pubmed/24270516
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ni.2766
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