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Extrasynaptic GABA(A) receptors in mediodorsal thalamic nucleus modulate fear extinction learning

BACKGROUND: The gamma-amino-butyric acid (GABA) system is a critical mediator of fear extinction process. GABA can induce “phasic” or “tonic” inhibition in neurons through synaptic or extrasynaptic GABA(A) receptors, respectively. However, role of the thalamic “tonic GABA inhibition” in cognition ha...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Paydar, Afshin, Lee, Boyoung, Gangadharan, Gireesh, Lee, Sukchan, Hwang, Eun Mi, Shin, Hee-Sup
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4066285/
https://ncbi.nlm.nih.gov/pubmed/24886120
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-6606-7-39
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