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Extrasynaptic GABA(A) receptors in mediodorsal thalamic nucleus modulate fear extinction learning

BACKGROUND: The gamma-amino-butyric acid (GABA) system is a critical mediator of fear extinction process. GABA can induce “phasic” or “tonic” inhibition in neurons through synaptic or extrasynaptic GABA(A) receptors, respectively. However, role of the thalamic “tonic GABA inhibition” in cognition ha...

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Detalhes bibliográficos
Main Authors: Paydar, Afshin, Lee, Boyoung, Gangadharan, Gireesh, Lee, Sukchan, Hwang, Eun Mi, Shin, Hee-Sup
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4066285/
https://ncbi.nlm.nih.gov/pubmed/24886120
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-6606-7-39
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