let-7 Enhances Osteogenesis and Bone Formation While Repressing Adipogenesis of Human Stromal/Mesenchymal Stem Cells by Regulating HMGA2

Bone and fat cells share a common progenitor, stromal/mesenchymal stem cells (MSCs), that can differentiate into osteoblasts or adipocytes. Osteogenesis and adipogenesis of MSCs maintain homeostasis under physiological conditions. The disruption of this homeostasis leads to bone-related metabolic di...

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Hlavní autoři: Wei, Jianfeng, Li, Hongling, Wang, Shihua, Li, Tangping, Fan, Junfen, Liang, Xiaolei, Li, Jing, Han, Qin, Zhu, Li, Fan, Linyuan, Zhao, Robert Chunhua
Médium: Artigo
Jazyk:Inglês
Vydáno: Mary Ann Liebert, Inc. 2014
Témata:
Original Research Reports
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4066225/
https://ncbi.nlm.nih.gov/pubmed/24617339
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/scd.2013.0600
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