let-7 Enhances Osteogenesis and Bone Formation While Repressing Adipogenesis of Human Stromal/Mesenchymal Stem Cells by Regulating HMGA2

Bone and fat cells share a common progenitor, stromal/mesenchymal stem cells (MSCs), that can differentiate into osteoblasts or adipocytes. Osteogenesis and adipogenesis of MSCs maintain homeostasis under physiological conditions. The disruption of this homeostasis leads to bone-related metabolic di...

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Detalhes bibliográficos
Main Authors: Wei, Jianfeng, Li, Hongling, Wang, Shihua, Li, Tangping, Fan, Junfen, Liang, Xiaolei, Li, Jing, Han, Qin, Zhu, Li, Fan, Linyuan, Zhao, Robert Chunhua
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2014
Assuntos:
Original Research Reports
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4066225/
https://ncbi.nlm.nih.gov/pubmed/24617339
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/scd.2013.0600
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