Structural and degradative aspects of ornithine decarboxylase antizyme inhibitor 2

Ornithine decarboxylase (ODC) is the key enzyme in the polyamine biosynthetic pathway. ODC levels are controlled by polyamines through the induction of antizymes (AZs), small proteins that inhibit ODC and target it to proteasomal degradation without ubiquitination. Antizyme inhibitors (AZIN1 and AZI...

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Autors principals: Ramos-Molina, Bruno, Lambertos, Ana, Lopez-Contreras, Andrés J., Kasprzak, Joanna M., Czerwoniec, Anna, Bujnicki, Janusz M., Cremades, Asunción, Peñafiel, Rafael
Format: Artigo
Idioma:Inglês
Publicat: Elsevier 2014
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4066113/
https://ncbi.nlm.nih.gov/pubmed/24967154
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.fob.2014.05.004
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