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Structural and degradative aspects of ornithine decarboxylase antizyme inhibitor 2
Ornithine decarboxylase (ODC) is the key enzyme in the polyamine biosynthetic pathway. ODC levels are controlled by polyamines through the induction of antizymes (AZs), small proteins that inhibit ODC and target it to proteasomal degradation without ubiquitination. Antizyme inhibitors (AZIN1 and AZI...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Elsevier
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4066113/ https://ncbi.nlm.nih.gov/pubmed/24967154 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.fob.2014.05.004 |
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