Structural and degradative aspects of ornithine decarboxylase antizyme inhibitor 2

Ornithine decarboxylase (ODC) is the key enzyme in the polyamine biosynthetic pathway. ODC levels are controlled by polyamines through the induction of antizymes (AZs), small proteins that inhibit ODC and target it to proteasomal degradation without ubiquitination. Antizyme inhibitors (AZIN1 and AZI...

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Main Authors: Ramos-Molina, Bruno, Lambertos, Ana, Lopez-Contreras, Andrés J., Kasprzak, Joanna M., Czerwoniec, Anna, Bujnicki, Janusz M., Cremades, Asunción, Peñafiel, Rafael
Format: Artigo
Language:Inglês
Published: Elsevier 2014
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4066113/
https://ncbi.nlm.nih.gov/pubmed/24967154
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.fob.2014.05.004
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