Solubility and Bioavailability Enhancement of Poorly Aqueous Soluble Atorvastatin: In Vitro, Ex Vivo, and In Vivo Studies

The objective of this investigation was to improve the solubility of the poorly water soluble drug atorvastatin (ATR), using solid dispersion (SD) techniques, with Neem Gum (NG) as a hydrophilic carrier. The effects of the polymer concentration and method of preparation on the solubility and dissolu...

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Detaylı Bibliyografya
Asıl Yazarlar: Rodde, Madhuri S., Divase, Ganesh T., Devkar, Tejas B., Tekade, Avinash R.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Hindawi Publishing Corporation 2014
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4065680/
https://ncbi.nlm.nih.gov/pubmed/24995297
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2014/463895
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