MiR-15b Targets Cyclin D1 to Regulate Proliferation and Apoptosis in Glioma Cells

Aim. To investigate the role and mechanism of miR-15b in the proliferation and apoptosis of glioma. Methods. The miR-15b mimics were transfected into human glioma cells to upregulate the miR-15b expression. Cyclin D1 was determined by both western blotting analysis and luciferase reporter assay. Met...

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Autors principals: Sun, Guan, Shi, Lei, Yan, Shushan, Wan, Zhengqiang, Jiang, Nan, Fu, Linshan, Li, Min, Guo, Jun
Format: Artigo
Idioma:Inglês
Publicat: Hindawi Publishing Corporation 2014
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4065679/
https://ncbi.nlm.nih.gov/pubmed/24995320
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2014/687826
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