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Dopamine denervation of the prefrontal cortex increases expression of the astrocytic glutamate transporter GLT-1

Both dopamine and glutamate are critically involved in cognitive processes such as working memory. Astrocytes, which express dopamine receptors, are essential elements in the termination of glutamatergic signaling: the astrocytic glutamate transporter GLT-1 is responsible for >90% of cortical glu...

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Autors principals: Vollbrecht, Peter J., Simmler, Linda D., Blakely, Randy D., Deutch, Ariel Y.
Format: Artigo
Idioma:Inglês
Publicat: 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4065617/
https://ncbi.nlm.nih.gov/pubmed/24611756
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jnc.12697
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