MicroRNA response to hypoxic stress in soft tissue sarcoma cells: microRNA mediated regulation of HIF3α

BACKGROUND: Hypoxia is often encountered in solid tumors and known to contribute to aggressive tumor behavior, radiation- and chemotherapy resistance resulting in a poor prognosis for the cancer patient. MicroRNAs (miRNAs) play a role in the regulation of the tumor cell response to hypoxia, however,...

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Autors principals: Gits, Caroline MM, van Kuijk, Patricia F, de Rijck, Jonneke CWM, Muskens, Nikky, Jonkers, Moniek BE, van IJcken, Wilfred F, Mathijssen, Ron HJ, Verweij, Jaap, Sleijfer, Stefan, Wiemer, Erik AC
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2014
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4065608/
https://ncbi.nlm.nih.gov/pubmed/24927770
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-14-429
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