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Histone/protein deacetylase SIRT1 is an anticancer therapeutic target
SIRT1, a member of the NAD(+)-dependent histone/protein deacetylase family, is involved in chromatin remodeling, DNA repair, and stress response and is a potential drug target. 5-fluorouracil (FU) and the S(N)1-type DNA methylating agent temozolomide (TMZ) are anticancer agents. In this study, we de...
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Main Authors: | , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
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e-Century Publishing Corporation
2014
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4065402/ https://ncbi.nlm.nih.gov/pubmed/24959376 |
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