Biomarkers measured in buccal and blood leukocyte DNA as proxies for colon tissue global methylation

There is increasing interest in clarifying the role of global DNA methylation levels in colorectal cancer (CRC) etiology. Most commonly, in epidemiologic studies, methylation is measured in DNA derived from blood leukocytes as a proxy measure of methylation changes in colon tissue. However, little i...

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Main Authors: Ashbury, Janet E, Taylor, Sherryl A, Tse, M Yat, Pang, Stephen C, Louw, Jacob A, Vanner, Stephen J, King, Will D
Format: Artigo
Jezik:Inglês
Izdano: e-Century Publishing Corporation 2014
Teme:
Brief Communication
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4065400/
https://ncbi.nlm.nih.gov/pubmed/24959316
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