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Biomarkers measured in buccal and blood leukocyte DNA as proxies for colon tissue global methylation

There is increasing interest in clarifying the role of global DNA methylation levels in colorectal cancer (CRC) etiology. Most commonly, in epidemiologic studies, methylation is measured in DNA derived from blood leukocytes as a proxy measure of methylation changes in colon tissue. However, little i...

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Detalhes bibliográficos
Main Authors: Ashbury, Janet E, Taylor, Sherryl A, Tse, M Yat, Pang, Stephen C, Louw, Jacob A, Vanner, Stephen J, King, Will D
Formato: Artigo
Idioma:Inglês
Publicado em: e-Century Publishing Corporation 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4065400/
https://ncbi.nlm.nih.gov/pubmed/24959316
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