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The U5 snRNA Internal Loop 1 Is a Platform for Brr2, Snu114 and Prp8 Protein Binding During U5 snRNP Assembly

The U5 small nuclear ribonucleoprotein particle (snRNP) forms the heart of the spliceosome which is required for intron removal from pre-mRNA. The proteins Prp8, Snu114 and Brr2 all assemble with the U5 small nuclear RNA (snRNA) to produce the U5 snRNP. Successful assembly of the U5 snRNP, then inco...

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Detalhes bibliográficos
Main Authors: Nancollis, Verity, Ruckshanthi, Jayalath PD, Frazer, Lily Novak, O'Keefe, Raymond T
Formato: Artigo
Idioma:Inglês
Publicado em: BlackWell Publishing Ltd 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4065371/
https://ncbi.nlm.nih.gov/pubmed/23857713
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcb.24625
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