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Dissecting the functional role of different isoforms of the L-type Ca(2+) channel

There currently exist a great number of different mouse lines in which the activity of a particular gene of interest has been inactivated or enhanced. However, it is also possible to insert specific mutations in a gene so that the pharmacological sensitivity of the gene product is altered. An exampl...

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Bibliografske podrobnosti
Main Authors: Bourinet, Emmanuel, Mangoni, Matteo E., Nargeot, Joël
Format: Artigo
Jezik:Inglês
Izdano: American Society for Clinical Investigation 2004
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC406536/
https://ncbi.nlm.nih.gov/pubmed/15146233
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI200421815
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