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Dissecting the functional role of different isoforms of the L-type Ca(2+) channel
There currently exist a great number of different mouse lines in which the activity of a particular gene of interest has been inactivated or enhanced. However, it is also possible to insert specific mutations in a gene so that the pharmacological sensitivity of the gene product is altered. An exampl...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Clinical Investigation
2004
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC406536/ https://ncbi.nlm.nih.gov/pubmed/15146233 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI200421815 |
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