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Antagonistic antibody prevents toll-like receptor 2–driven lethal shock-like syndromes
Hyperactivation of immune cells by bacterial products through toll-like receptors (TLRs) is thought of as a causative mechanism of septic shock pathology. Infections with Gram-negative or Gram-positive bacteria provide TLR2-specific agonists and are the major cause of severe sepsis. In order to inte...
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| Main Authors: | , , , , , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Clinical Investigation
2004
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC406529/ https://ncbi.nlm.nih.gov/pubmed/15146245 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI200420762 |
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