Leukocyte-adjusted epigenome-wide association studies of blood from solid tumor patients

Epigenome-wide studies of DNA methylation using blood-derived DNA from cancer patients are complicated by the heterogeneity of cell types within blood and the associated cell lineage specification of DNA methylation signatures. Here, we applied a novel set of analytic approaches to assess the associ...

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Detalhes bibliográficos
Main Authors: Langevin, Scott M, Houseman, E Andres, Accomando, William P, Koestler, Devin C, Christensen, Brock C, Nelson, Heather H, Karagas, Margaret R, Marsit, Carmen J, Wiencke, John K, Kelsey, Karl T
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2014
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4065186/
https://ncbi.nlm.nih.gov/pubmed/24671036
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/epi.28575
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