Peripheral blood immune cell methylation profiles are associated with non-hematopoietic cancers

BACKGROUND: Blood leukocytes from patients with solid tumors exhibit complex and distinct cancer-associated patterns of DNA methylation. However, the biological mechanisms underlying these patterns remain poorly understood. Since epigenetic biomarkers offer significant clinical potential for cancer...

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Autori principali: Koestler, Devin C., Marsit, Carmen J., Christensen, Brock C., Accomando, William, Langevin, Scott M., Houseman, E. Andres, Nelson, Heather H., Karagas, Margaret R., Wiencke, John K., Kelsey, Karl T.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2012
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3415587/
https://ncbi.nlm.nih.gov/pubmed/22714737
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1055-9965.EPI-12-0361
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