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Frequent promoter hypermethylation and expression reduction of the glucocorticoid receptor gene in breast tumors

Previous studies have found that expression of the Glucocorticoid Receptor (GR) is altered or reduced in various cancers, while the GR promoter has been shown to be methylated in gastric, lung, and colorectal cancers. Examining a small cohort of matched normal and breast cancer samples we found that...

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Autori principali: Nesset, Kirsten A, Perri, Ami M, Mueller, Christopher R
Natura: Artigo
Lingua:Inglês
Pubblicazione: Landes Bioscience 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4065183/
https://ncbi.nlm.nih.gov/pubmed/24622770
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/epi.28484
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