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The localization of histone H3K27me3 demethylase Jmjd3 is dynamically regulated
Jmjd3 is required for cellular differentiation and senescence, and inhibits the induction of pluripotent stem cells by demethylating histone 3 lysine 27 trimethylation (H3K27me3). Although recent studies reveal crucial biological roles for Jmjd3, it is unclear how its demethylase activity is control...
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Landes Bioscience
2014
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4065181/ https://ncbi.nlm.nih.gov/pubmed/24646476 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/epi.28524 |
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