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The localization of histone H3K27me3 demethylase Jmjd3 is dynamically regulated

Jmjd3 is required for cellular differentiation and senescence, and inhibits the induction of pluripotent stem cells by demethylating histone 3 lysine 27 trimethylation (H3K27me3). Although recent studies reveal crucial biological roles for Jmjd3, it is unclear how its demethylase activity is control...

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Bibliografiske detaljer
Main Authors: Kamikawa, Yasunao F, Donohoe, Mary E
Format: Artigo
Sprog:Inglês
Udgivet: Landes Bioscience 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4065181/
https://ncbi.nlm.nih.gov/pubmed/24646476
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/epi.28524
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