Nalaganje...

Forced expression of DNA methyltransferases during oocyte growth accelerates the establishment of methylation imprints but not functional genomic imprinting

In mammals, genomic imprinting governed by DNA methyltransferase DNMT3A and its cofactor DNMT3L is essential for functional gametes. Oocyte-specific methylation imprints are established during oocyte growth concomitant with DNMT3A/DNMT3L expression, although the mechanisms of oocyte-specific imprint...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
Main Authors: Hara, Satoshi, Takano, Takashi, Fujikawa, Tsugunari, Yamada, Munehiro, Wakai, Takuya, Kono, Tomohiro, Obata, Yayoi
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2014
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4065157/
https://ncbi.nlm.nih.gov/pubmed/24599402
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddu100
Oznake: Označite
Brez oznak, prvi označite!