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Enhanced Ca(2+) influx from STIM1–Orai1 induces muscle pathology in mouse models of muscular dystrophy
Muscular dystrophy is a progressive muscle wasting disease that is thought to be initiated by unregulated Ca(2+) influx into myofibers leading to their death. Store-operated Ca(2+) entry (SOCE) through sarcolemmal Ca(2+) selective Orai1 channels in complex with STIM1 in the sarcoplasmic reticulum is...
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| Autors principals: | , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Oxford University Press
2014
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4065147/ https://ncbi.nlm.nih.gov/pubmed/24556214 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddu079 |
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