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Mechanism for Adhesion G Protein-Coupled Receptor GPR56-Mediated RhoA Activation Induced By Collagen III Stimulation

GPR56 is a member of the adhesion G protein-coupled receptor (GPCR) family. Despite the importance of GPR56 in brain development, where mutations cause a devastating human brain malformation called bilateral frontoparietal polymicrogyria (BFPP), the signaling mechanism(s) remain largely unknown. Lik...

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Detalhes bibliográficos
Main Authors: Luo, Rong, Jeong, Sung-Jin, Yang, Annie, Wen, Miaoyun, Saslowsky, David E., Lencer, Wayne I., Araç, Demet, Piao, Xianhua
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4065004/
https://ncbi.nlm.nih.gov/pubmed/24949629
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0100043
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