Morphine Enhances HIV-1(SF162)-Mediated Neuron Death and Delays Recovery of Injured Neurites

HIV-1 enters the CNS soon after initial systemic infection; within the CNS parenchyma infected and/or activated perivascular macrophages, microglia and astrocytes release viral and cellular toxins that drive secondary toxicity in neurons and other cell types. Our previous work has largely modeled HI...

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Detalhes bibliográficos
Main Authors: Masvekar, Ruturaj R., El-Hage, Nazira, Hauser, Kurt F., Knapp, Pamela E.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4064991/
https://ncbi.nlm.nih.gov/pubmed/24949623
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0100196
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