Fractalkine/CX(3)CL1 protects striatal neurons from synergistic morphine and HIV-1 Tat-induced dendritic losses and death

BACKGROUND: Fractalkine/CX(3)CL1 and its cognate receptor CX(3)CR1 are abundantly expressed in the CNS. Fractalkine is an unusual C-X3-C motif chemokine that is important in neuron-microglial communication, a co-receptor for HIV infection, and can be neuroprotective. To assess the effects of fractal...

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Главные авторы: Suzuki, Masami, El-Hage, Nazira, Zou, Shiping, Hahn, Yun-Kyung, Sorrell, Mary E, Sturgill, Jamie L, Conrad, Daniel H, Knapp, Pamela E, Hauser, Kurt F
Формат: Artigo
Язык:Inglês
Опубликовано: BioMed Central 2011
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Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3287119/
https://ncbi.nlm.nih.gov/pubmed/22093090
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1750-1326-6-78
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